As of today, the most credible scientific paradigm pertaining to the origin of life on Earth is undoubtedly the RNA World scenario.It is built on the assumption that catalytically active replicators (most probably RNA-like macromolecules) may have been responsible for booting up life almost four billion years ago.The many different incarnations of
Abstract Concomitant chromatin assembly and DNA duplication is essential for cell survival and genome integrity, and requires newly synthesized histones.Although the N-terminal domains of newly synthesized H3 wella color touch 77 45 and H4 present critical functions, their requirement for replication-coupled chromatin assembly is controversial.Usin
Erica Locatelli,1,* Yan Li,2,* Ilaria Monaco,1 Wei Guo,3 Mirko Maturi,1 Luca Menichetti,4 Paolo Armanetti,4 Robert C Martin,2 Mauro Comes Franchini1 1Department of Industrial Chemistry “Toso Montanari”, Bologna, Italy; 2Department of Surgery, School of Medicine, University of Louisville, Louisville, KY, USA; 3Department of tokidoki hell
A changing global climate can threaten the diversity of species and ecosystems.We explore the consequences of catastrophic disturbances in determining the evolutionary and demographic histories of secluded marble trout populations in Slovenian streams subjected to weather extremes, in particular recurrent flash floods and debris flows causing massi
Bilateral epididymal cysts are rare in childhood.Clinically they may present as acute scrotum and should be differentiated from grandpas best other pathologies.Here in, we report bilateral epididymal cysts in a 14-year-old boy.He was admitted to emergency department with symptoms of acute left scrotum.There was no history of trauma or infection.Blo